Research

Research in stress management:

Scientists have isolated novel phytochemicals in Ocimum sanctum that help in reducing risk of stress-related health problems. Experimental studies have shown that the active constituents of the herb help in reversing changes in the brain induced by stress. Treatment with Ocimum sanctum helped in reducing the elevated plasma corticosterone level. It also helped in increasing the serotonin, dopamine and noradrenaline levels in the brain. (Ahmad A et al. “Novel Ocimumoside A and B as anti-stress agents: modulation of brain monoamines and antioxidant systems in chronic unpredictable stress model in rats.” Phytomedicine. 2012 May).

Research to attenuate stress-related anxiety and depression:

Stress is one of the leading causes of anxiety and depression. According to experimental studies, by reversing stress-induced changes, Ocimum sanctum helps in reducing anxiety and depression. (Tabassum I et al. “Effects of Ocimum sanctum and Camellia sinensis on stress-induced anxiety and depression in male albino Rattus norvegicus.” Indian J Pharmacol. 2010 Oct).

Antibacterial activity:

Studies have revealed the antibacterial activity of Ocimum sanctum. It exhibited antibacterial activity against staphylococcal and other common bacterial infections. In addition, the analgesic and anti-inflammatory activities of the herb help in providing relief from the symptoms of the bacterial infections. (Singh S et al. “Antibacterial activity of Ocimum sanctum L. fixed oil.” Indian J Exp Biol. 2005 Sep).

Immunomodulatory activity:

Experimental studies have shown that treatment with Ocimum sanctum leaf extract promotes the phagocytic activities of lymphocytes and decreases bacterial count. (Mukherjee R at el. “Immunotherapeutic potential of Ocimum sanctum (L) in bovine subclinical mastitis.” Res Vet Sci. 2005 Aug).

Gastroprotective property:

Experimental studies have demonstrated the anti-ulcer activity of Ocimum sanctum. By improving mucus secretion and decreasing acid secretion, Ocimum sanctum leaf extract helps in inhibiting development of peptic ulcers. (Mandal S et al. “Ocimum sanctum Linn – a study on gastric ulceration and gastric secretion in rats.” Indian J Physiol Pharmacol. 1993 Jan).

Anti-diabetic activity:

Ocimum sanctum leaf extract helps in stimulating insulin secretion. Hence, it helps in lowering the blood sugar level and can be used for controlling diabetes. (Hannan JM et al. “Ocimum sanctum leaf extracts stimulate insulin secretion from perfused pancreas, isolated islets and clonal pancreatic beta cells. J. Endochrinol 2006).